Today's society is confronted with challenges in a number of key areas such as health, energy, and transport. The application areas of the DAI-Labor are tailored to design and develop ICT-based solutions towards addressing those challenges. To this end, the expertise and experience of researchers from different competence centers are integrated to ensure the applicability and practical relevance of research outcomes with this interdicisplinary approach. Each of these application areas at the DAI-Labor provides a common platform that supports inderdisciplinary work, synergies among researchers, and high-quality research results.